Monophysitism (from the Greekmonos meaning 'one, alone' and physis meaning 'nature'), or Monophysiticism, is the Christological position that Christ has only one nature (human-that-evolved-into-divine), as opposed to the Chalcedonian position which holds that Christ maintains two natures, one divine and one human. Monophysitism and its antithesis, Nestorianism, were both hotly disputed and divisive competing tenets in the maturing Christian traditions during the first half of the fifth century; during the tumultuous last decades of the Western Empire, and marked by the political shift in all things to a center of gravity then located in the Eastern Roman empire, and particularly in Syria, the Levant, and Anatolia, where Monophysitism was popular among the people.
There are two major doctrines that can indisputably be called Monophysite (English pronunciation: /məˈnɒfəsɪt/):
Eutychianism holds that the human and divine natures of Christ were fused into one new single (mono) nature: His human nature was "dissolved like a drop of honey in the sea".
Apollinarism or Apollinarianism holds that Christ had a human body and human "living principle" but that the Divine Logos had taken the place of the nous, or "thinking principle", analogous but not identical to what might be called a mind in the present day.
Monophysitism's theological point of view is also rejected by the Oriental Orthodox Churches, but was widely accepted in Syria and the Levant, leading to many tensions in the early days of the Byzantine Empire.
Later, Monothelitism was developed as an attempt to bridge the gap between the Monophysite and the Chalcedonian position, but it too was rejected by the members of the Chalcedonian synod, despite at times having the support of the Byzantine emperors and once escaping the condemnation of a Pope of Rome, Honorius I. Some are of the opinion that Monothelitism was at one time held by the Maronites, but the Maronite community, for the most part, dispute this, stating that they have never been out of communion with the Catholic Church.